Vol 5, No 1 (2018) > Articles >

Evaluasi Rasionalitas Penggunaan Obat Antihipertensi di Puskesmas Siantan Hilir Kota Pontianak Tahun 2015

Eka Kartika Untari , Alvani Renata Agilina , Ressi Susanti


Abstract: Hypertension is widely known as cardiovascular disease. In addition to resulting heart failure, hypertension can result in kidney failure and cerebrovascular disease. This study was aimed to determine the percentage of treatment rationality of hypertensive patient treatment outpatient in Puskesmas Siantan Hilir Pontianak 2015 which includes the appropriate indication, appropriate drug, appropriate patient, and appropriate dose based on the guideline JNC 7. This study was cross-sectional observational study using retrospective data such as medical records of outpatient hypertension patients in 2015. The total of sample for this research were 92 people. The percentage of using the angiotensin converting enzym inhibitor (captopril) was 47,46%; calcium channel blocker (amlodipine) was 34,75%; tiazid diuretic (hydrochlorothiazid) was 16,10%; loop diuretic (furosemid) was 0, 85%; and potassium sparing (spironolactone) was 0.85%. The therapy rasionality of hypertensive patients in this research were 100% appropriate indication, 70,65% appropriate drug, 100% appropriate patient and 98,91% appropriate dose. The conclusion of this study is that overall treatment that meets all four rational treatment criteria is 69.56%.

Keywords: antihipertensi; hipertensi; penggunaan obat rasional; antihypertension; hypertension; rationality

Published at: Vol 5, No 1 (2018) pages: 32-39

DOI: 10.7454/psr.v5i1.3870

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Chobaniam AV et al. (2003). Seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure. JAMA, 289, 2560-2572

Departemen Kesehatan RI. (2011). Kebijakan obat nasional. Jakarta: Departemen Kesehatan RI

Dinas Kesehatan Kota Pontianak. (2015). Profil Kesehatan Kota Pontianak 2014. Pontianak: Dinas Kesehatan Kota Pontianak.

Dinas Kesehatan Kota Pontianak. (2011). Profil Kesehatan Kota Pontianak 2010. Pontianak: Dinas Kesehatan Kota Pontianak.

Dipiro JT, Talbert RL, Yee GC, Matzke GR, Wells BG, Posey LM. (2008). Pharmacotherapy: A Phatophysiologic Approach. Seventh Edition. USA: MC Graw-Hill.

Hilal-Dandan R, & Brunton L. (2013). Goodman and Gilman manual of pharmacology and therapeutics. McGraw Hill Professional.

Kardela W, Andrajati R, Sudibyo S. (2014). Perbandingan penggunaan obat rasional berdasarkan indikator WHO di puskesmas kecamatan antara kota Depok dan Jakarta Selatan. Jurnal Kefarmasian Indonesia, 4 (2), 91-102.

Kemenkes RI. (2011). Modul penggunaan obat rasional. Jakarta: Kementrian Kesehatan RI.

Kemenkes RI. (2013). Laporan riskesdas 2013. Jakarta: Badan Litbangkes Kemenkes RI.

Oktora R. (2007). Gambaran penderita hipertensi yang dirawat inap di bagian penyakit dalam RSUD Arifin Achmad Pekanbaru periode Januari sampai Desember 2005. Skripsi. FK UNRI.

Oparil S, Zaman MA, Calhoun DA. (2003). Pathogenesis of hypertension. Ann Intern Med, 139, 761-776.

Rosano GMC, Vitale C, Marazzi G, Volterrani M. (2007). Menopause and cardiovascular disease: The evidence. Climacteric, 10(sup1), 19-24.

World Health Organization. (1993). How to investigate drug use in health facilities. Geneva: World Health Organization.

World Health Organization. (1999). Indicators for monitoring national drug policy. (2nd ed). Geneva

World Health Organization. (2004). Promoting rational use of medicines saves lives and money WHO experts say. Geneva.

World Health Organization. (2002). Promoting rational use of medicines: core components. Geneva