Vol 1, No 3 (2014) > Articles >

Formulasi Krim Antioksidan Ekstrak Etanol Daun Ubi Jalar Ungu (Ipomoea batatas (L.) Lamk) Sebagai Anti Aging

Damaranie Dipahayu , Widji Soeratri , Mangestuti Agil

 

Abstract:

Purple sweet potatoes leaves (Ipomoea batatas (L.) Lamk) Antin 3 variety (IBLA) are natural antioxidant sources because of anthocyanins contents. IBLA extracted by kinetic maseration with 70 % ethanolic solution. The aims of this research are to determine antioxidant activity for DPPH (2,2-diphenyl-1-picrylhydrazil) scavenging activity and formulating IBLA extract into oil in water base cream dosage form. Both the base cream and formulation were stored at 28ºC for a period of 4 weeks to predict their stability. The evaluation parameters consisted of organoleptic, homogenity, pH value, viscosity, emulsion type, dispersive power, mechanic and freeze and thaw. Futhermore, the base cream and formulation were evaluated for their effects on skin moisture, curvature and pigmentation. The results showed that ethanolic extract of IBLA had antioxidant activity of 80.43 % compared with pure vitamin C. IC 50 value of IBLA extract is 3.68 ppm while vitamin C is   2.96 ppm. Base and antioxidant creams had      a physical stability for 4 weeks. The base and antioxidant creams have no effect on promoting skin moisture. The base cream had no effect in inhibiting curvature but antioxidant cream was effective to inhibit curvature. The base showed no pigmentation inhibiting effect but antioxidant cream was effective in inhibiting pigmentation.


Keywords: antioxidant, IBLA, o/w cream, skin moisture,curvature,pigmentation.

Published at: Vol 1, No 3 (2014) pages: 166-179

DOI: 10.7454/psr.v1i3.3485


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References:

Almeida, I., Valentao, P., Andrade, P. (2008). In vivo skin irritation potential of a Castanea sativa (chesnut) leaf extract, a putative natural antioxidant for topical application. Basic Clinical Pharmacology Toxicology, 103(5), 461- 467

Bernatoniene, J., Masteikova, R., Davalgiene, J., Peciura, R., Gauryliene, R., Bernatoniene, R. (2011). Topical Apllication Of Calendula officinalis (L.) ; Formulation and Evaluation of Hydrophilic With Antioxidant Activity. Journal of Medicinal Plants Research, 5(6), 868-877

Colipa Guidelines. (2004). Guideliness For The Stability Testing of Cosmetic Product. The European Cosmetics Association.

Colipa Guidelines. (2008). Guideliness For The Evaluation of The Efficacy of Cosmetic Product. The European Cosmetics Association.

Draelos, Z.D., Pugliese, P.T. (2011). Physiology of the Skin (3rd Ed.) USA : Allured Bussiness Media

Farida, R., Mimi, A., Nurwani, P.A .(2011). Formulasi Krim Ekstrak Etanol Daun Ubi Jalar (Ipomoeae batatas L.) Untuk Pengobatan Luka Bakar. Scientia, 1( 1)

Ghasemzadeh, A., Omidvar, V., Jaafar, H .Z. E. ( 2012) . Polyphenolic content and their antioxidant activity inleaf extract of sweet potato (Ipomoea batatas). Journal of Medicinal Plants Research, 6(15), 2971-2976

Gozali, D., Abdassah, M., Subghan, A., Al Lathiefah, S. (2009). Formulasi Krim Pelembab Wajah yang Mengandung Tabir Surya Nanopartikel Zink Oksida Salut Silikon. Farmaka, 7 (1).

Lambers, H., Piessens, S., Bloem, A., Pronk, H., Finke,l P. (2006). Natural skin surface pH is on average below 5, which is beneficial for its resident flora. International Journal Cosmetics Science, 28(5), 359- 370.

Mun, H.S., Boyce, N.A., Somasundram. (2012). Antioxidant activity, phenolic and flavonoid content in the leaves of different varieties of sweet potatoes (Ipomoea batatas). Australian Journal of Crop Science, 6 (3), 375-380.

Pinnel, S. (2003) .Cutaneous Photodamage, Oxidative Stress, and Topical Antioxidant Protection. Retrieved from American Academy of Dermatology, Inc. Website: pinne002@ mc.duke.edu. http://skin-care.health- cares.net/oily-skin-care.php

Poljsak, B., Dahmane, R.(2012). Free Radicals and Extrinsic Skin Aging. DermatolResearchandPractice.Website: http://dx.doi.org/10.1155/2012/135206.

Rasul, A., Akhtar., N. (2012). Anti Aging Potential Of Cream Containing Milk Thistle Extract : Formulation and In Vivo Evaluation. African Journal of Biotechnology, 11(6), 1509- 1515.

Ratnam, D., Ankola, D., Bhardjaw, V., Sahana, D., Kumar, M. (2006). Role of antioxidant in prophylaxis and therapy : A pharmaceutical prespective. Journal Control Release, 113(3), 189-207.

Trifena. (2012). Analisis Uji In Vitro dan In Vivo Ekstrak Kombinasi Kulit Manggis (Garcinia mangostana L.) Dan Pegagan (Centella asiatica L) Sebagai Krim Antioksidan. Tesis. Universitas Indonesia.

Thornfeldt, C., Bourne, K. (2010). The New Ideal in Skin Health :Separating Fact from Fiction Practical Application of the Science of Skin Care. Allured Business Media.Carol Stream, USA.

Yusuf., Ginting, E., Rahmi,Y., Restuono, J. (2013). Antin-2 dan Antin-3, Varietas Unggul Ubijalar Ungu Kaya Antosianin Sebagai Pangan Sehat Menyehatkan. Website: http://balitkabi.litbang.deptan. go.id : 20/11/2013