Vol 7, No 1 (2010) > Articles >

Penelitian Antiimplantasi Ekstrak Etanol Daging Buah Burahol (Stelechocarpus burahol Hook F. & Thomson) Pada Tikus Putih

Clara Sunardi , Sri Sumiwi , Ai Hertati

 

Abstract:

We examined antiimplantation effect of ethanol extract from ripening burahol flesh
(Stelechocarpus burahol Hook f. & Thomson) using doses 1g and 0.5g per Kg Body
Weight (BW) on White Female Rats Wistar Strain. The ethanol extract was given
orally on daily basis from diestrus phase until 7th day of pregnancy. Two parameter
used in this investigation were number of implants and number of born fetus. The
fetus were examined by observing their morphology to identify the existence of teratogenic
effect. The result showed that the two doses reduced both the number of implants
and born fetus significantly. In addition, the burahol flesh as an antifertility
agent has two functions: as antiimplantation and abortifacient. Lastly morphological
examination on the fetus did not show any teratogenic effect.


Keywords: Burahol (Stelechocarpus burahol Hook f. & Thomson), antiimplantation.


Published at: Vol 7, No 1 (2010) pages: 1-8

DOI: 10.7454/psr.v7i1.3445


Access Counter: 818 views

Full PDF Download