Vol 3, No 3 (2006) > Articles >

UJI HAMBATAN TUMORIGENESIS SARI BUAH MERAH (PANDANUS CONOIDEUS LAM.) TERHADAP TIKUS PUTIH BETINA YANG DIINDUKSI 7,12 DIMETILBENZ(a)ANTRASEN (DMBA)

Abdul Munim , Retnosari Andrajati , Heni Susilowati

 

Abstract: Red fruit (Pandanus conoideous Lam.) has been known by public as a medicine for any kind of diseases, among of them is for cancer. To determine the carcinogenesis
inhibition effect of red fruit extract , we have examined the effect on 7,12- dimethylbenz[a]anthrasene (DMBA)-induced rat lungs cancer model in female Sprague-Dawley rats. The extract was tested at 0.21 ml/200 g bw; 0.43 ml/200 g bw
and 0.88 ml/ 200 g bw. The experiment was terminated at day 120. Lung histology was used to evaluate carcinogenesis inhibition. The result showed that the extract at 0.21 ml/200g bw improved lung carcinogenesis inhibition than other dose.
Key words : red fruit extract, DMBA, lung cancer, Pandanus conoideus

Published at: Vol 3, No 3 (2006) pages: 153-161

DOI: 10.7454/psr.v3i3.3407


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